Tretinoin topical (for the skin) is used to treat acne, to smooth rough facial skin, and to reduce the appearance of fine wrinkles and mottled skin discoloration.
Generic Flexeril is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Generic Flexeril is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.