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Generic Vasotec is used for treating high blood pressure, heart failure, and other heart problems. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by helping to relax blood vessels.

Generic Zestoretic is used to treat hypertension (high blood pressure). Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Lisinopril lowers blood pressure and also relieves symptoms of fluid retention.