Generic Imitrex is used for the treatment of migraine headaches with or without aura (eg, flashing lights, wavy lines, dark spots). An aura is a strange feeling or visual disturbance that warns you of an attack. It is not used to prevent migraines.
Generic Zestoretic is used to treat hypertension (high blood pressure). Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Lisinopril lowers blood pressure and also relieves symptoms of fluid retention.